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Nebivolol - sotalol- محاضرة 6

محاضرة رقم 6
Nebivolol - sotalol

المحاضرة دى هنخلص البيتا بلوكرز


Nebivolol  1-

2- sotalol

ودول ادويتهم فى السوق قليلة



Nebivolol  1-

class: is a β1 receptor blocker with nitric oxide potentiating vasodilatory effect





ده  شبيه بالظبط ل

atenolol
Bisoprolol
Misoprolol

فى محاضرات 1و2و3

الادوية فى السوق المصرى






Indication  and Dose

. Hypertension
5mg daily
ELDERLY initially 2.5mg
daily, increased if necessary to 5mg daily



. Adjunct in heart failure




,initially
1.25 mgOnce daily  ,then if tolerated increased at
Intervals of 1–2weeks to 2.5 mg once daily,then to
5mg once daily ,then to max. 10 mg once daily

لمعرفة باقى تفاصيل الدواء

ذاكر محاضرة 1و2و3 تعتبر

خلصت كده

Nebivolol


2- sotalol

class: non-selective competitive β- receptor blockers, an antiarrhythmic drug  (cardiac action potential duration prolongation) properties


الادوية فى السوق المصرى



Indications

life-threatening arrhythmias including
Ventricular tachyarrhythmias ;symptomatic

non-sustained ventricular tachy arrhythmias



Dose

. By mouth with ECG monitoring and measurement of
Corrected QT interval ,


arrhythmias
, initially 80 mg
Daily in 1–2 divided doses increased gradually at
Intervals of 2–3 days to usual dose of 160–320 mg
Daily in 2 divided doses ;higher doses of 480–640 mg
Daily for life-threatening ventricul ararrhythmias
Under specialist supervision

تحت اشراف الطبيب


ده شبيه ل
Cardvedilol
non-selective β- receptor blockers
محاضرة 4و5
هنذكر بس فروقات بسيطة

FDA pregnancy category B.

This medication is not expected to be harmful to an unborn baby.
Tell your doctor if you are pregnant or plan to become pregnant during treatment.


Sotalol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.


What happens if I miss a dose?
Take the missed dose as soon as you remember. If your next dose is less than 8 hours away, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What should I discuss with my healthcare provider before taking sotalol?
Do not use this medication if you are allergic to sotalol, or if you have:
  • certain heart conditions, especially "AV block" (unless you have a pacemaker);


  • a history of "Long QT syndrome"; or
severe or uncontrolled congestive heart failure.


  • an electrolyte imbalance such as low levels of potassium or magnesium in your blood;
food contain potasium

  • فى محاضرة5   contraindication وبقية

How should I take sotalol?
You will receive your first few doses of sotalol in a hospital setting where your heart can be monitored in case the medication causes serious side effects.


Take sotalol exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor
If there are any changes in the brand or strength of sotalol you use, your dosage needs may change

Take this medication with a full glass of water.

Take sotalol at the same time every day.

Do not skip doses or stop taking sotalol without first talking to your doctor. Stopping suddenly may make your condition worse

. You may need to use less and less before you stop the medication completely.


Tell your doctor if you have an illness that involves diarrhea or vomiting lasting more than a few hours. Prolonged diarrhea or vomiting can lower your potassium levels, making it dangerous for you to use sotalol.

قئ وترجيع

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your heart and kidney function will also need to be tested. Do not miss any scheduled visits to your doctor.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using sotalol.

If you need to have any type of surgery, you may need to temporarily stop using sotalol. Be sure the surgeon knows ahead of time that you are using sotalol

What should I avoid while taking sotalol?
Do not take an antacid within 2 hours before or after taking sotalol.
Avoid using antacids without your doctor's advice.
ادوية الحموضة



Use only the specific type of antacid your doctor recommends. Antacids contain different medicines and some types can make it harder for your body to absorb sotalol.
What other drugs will affect sotalol?
Tell your doctor about all other medications you use, especially:
  • a diuretic (water pill)
  • antibiotics such as azithromycin , clarithromycin , erythromycin , Erythrocin, telithromycin


  • a calcium channel blocker




وبقية الادوية فى محاضرة 5

Drug  Interactions

راجع محاضرة 4و5

side effects

راجع محاضرة 4و5




Refernce

Drugs.com
Bnf 61 book
Atlas


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